Yihong Fan Selected Research

4-aminopyrrolidine-2-carboxylic acid

1/2022

Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosis.

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Yihong Fan Research Topics

Disease

4	Abdominal Pain (Pain, Abdominal) 12/2022 - 01/2018
3	Pain (Aches) 12/2022 - 01/2009
3	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 01/2018
3	Crohn Disease (Crohn's Disease) 11/2019 - 01/2018
1	Abscess 11/2019
1	Fistula 11/2019
1	Glioblastoma (Glioblastoma Multiforme) 08/2019
1	Coronary Disease (Coronary Heart Disease) 01/2019
1	Wounds and Injuries (Trauma) 01/2019
1	Hemorrhage 01/2019
1	Ulcer 10/2018
1	Fibrosis (Cirrhosis) 06/2018
1	Immunoglobulin G4-Related Disease 06/2018
1	Atrophy 08/2017
1	Gastritis 08/2017
1	Metaplasia 08/2017
1	Stomach Neoplasms (Stomach Cancer) 08/2017
1	Esophageal Achalasia (Megaesophagus) 05/2016
1	Hypersensitivity (Allergy) 01/2015
1	Postoperative Pain 04/2012
1	Neuroblastoma 06/2011
1	Hyperalgesia 01/2009
1	Neuralgia (Stump Neuralgia) 01/2009
1	Neoplasms (Cancer) 06/2007

Drug/Important Bio-Agent (IBA)

2	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 01/2022 - 01/2018
2	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2020 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 11/2019 - 08/2018
1	CytokinesIBA 12/2022
1	salicylhydroxamic acid (SHAM)IBA 12/2022
1	TeaIBA 12/2022
1	4-aminopyrrolidine-2-carboxylic acidIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	GLPG2222IBA 01/2020
1	Infliximab (Remicade)FDA Link 11/2019
1	C-Reactive ProteinIBA 11/2019
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 08/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019
1	geranylgeranylacetone (teprenone)IBA 01/2019
1	Capsules (Microcapsules)IBA 10/2018
1	FibrinIBA 06/2018
1	Immunoglobulin G (IgG)IBA 06/2018
1	Benzoic Acid (Potassium Benzoate)FDA Link 01/2018
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2018
1	Protons (Proton)IBA 01/2018
1	SaltsIBA 01/2018
1	Glutamic Acid (Glutamate)FDA Link 01/2018
1	AnionsIBA 01/2018
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018
1	CreatineIBA 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	Indicators and Reagents (Reagents)IBA 08/2017
1	gastrin 17 (G 17)IBA 08/2017
1	Pepsinogen A (Pepsinogen)IBA 08/2017
1	Interleukin-4 (Interleukin 4)IBA 01/2015
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 06/2011
1	A-836339IBA 01/2009
1	Freund's AdjuvantIBA 01/2009
1	cyclopropanecarboxylic acidIBA 01/2009
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2009
1	CannabinoidsIBA 01/2009
1	AmidesIBA 01/2009
1	CB2 Cannabinoid ReceptorIBA 01/2009
1	Capsaicin (Zostrix)FDA Link 01/2009
1	SurvivinIBA 06/2007

Therapy/Procedure

1	Acupuncture Points (Acupuncture Point) 12/2022
1	Myotomy 05/2016
1	Analgesia 04/2012
1	Therapeutics 06/2007